Munotec reagents are non-human, non-mammalian fusion proteins that bind to the Fab of antibodies (e.g., IgG, IgA and IgM) of various species and block the antigen binding site.

Munotec proteins can:

  • serve as a surrogate antigen

  • neutralize antibody binding to antigen

  • confirm antibody binding and target specificity

  • capture and orient antibodies on solid matrices

  • differentiate antigen-engaged Fab from non-engaged Fab

  • detect antibodies in solution or in a solid matrix (e.g., bead, blot, wells, resin)

Enzyme (e.g., HRP)-Munotec or tag-Munotec proteins are available and offer limitless applications. Customized Munotec constructs are available.