Munotec reagents are non-human, non-mammalian fusion proteins that bind to the Fab of antibodies (e.g., IgG, IgA and IgM) of various species and block the antigen binding site.
Munotec proteins can:
serve as a surrogate antigen
neutralize antibody binding to antigen
confirm antibody binding and target specificity
capture and orient antibodies on solid matrices
differentiate antigen-engaged Fab from non-engaged Fab
detect antibodies in solution or in a solid matrix (e.g., bead, blot, wells, resin)
Enzyme (e.g., HRP)-Munotec or tag-Munotec proteins are available and offer limitless applications. Customized Munotec constructs are available.